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1

Characterization of the human γ-glutamyl hydrolase promoter and its gene expression in human tissues and cancer cell lines

Dezhong Yin, John Galivan, Wei Ao, Rong Yao

Journal:

Year:

2003

Language:

english

File:

PDF, 1.16 MB

english, 2003

2

Site-directed mutagenesis establishes cysteine-110 as essential for enzyme activity in human γ-glutamyl hydrolase

CHAVE, Karen J., GALIVAN, John, RYAN, Thomas J.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 126 KB

english, 1999

3

Proliferation-dependency of folylpolyglutamyl synthetase activity in maturating luminal epithelial cells of mouse small intestine

Francis M. Sirotnak, Thomas B. Johnson, Larry L. Samuels, John Galivan

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 395 KB

english, 1988

4

Insulin-dependent suppression in glutamyl hydrolase activity and elevated cellular methotrexate polyglutamates

John Galivan, Myung S. Rhee

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 586 KB

english, 1995

5

Reversibly permeable hepatoma cells in culture

Balinska, Malgorzata, Samsonoff, William A., Galivan, John

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1982

Language:

english

File:

PDF, 777 KB

english, 1982

6

Glutamyl hydrolase and the multitargeted antifolate LY231514

Myung S. Rhee, Thomas J. Ryan, John Galivan

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 172 KB

english, 1999

7

Folate analogs. 34. Synthesis and antitumor activity of non-polyglutamylatable inhibitors of dihydrofolate reductase

Abraham, Ann, McGuire, J. J., Galivan, John, Nimec, Zenia, Kisliuk, R. L., Gaumont, Y., Nair, M. G.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 858 KB

english, 1991

8

γ -fluoromethotrexate: Synthesis and Biological Activity of a Potent Inhibitor of Dihydrofolate Reductase with Greatly Diminished Ability to Form poly-γ -glutamates

John Galivan, James Inglese, John J. McGuire, Zenia Nimec and James K. Coward

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 890 KB

english, 1985

9

Interaction of methotrexate poly(l-lysine) with transformed hepatic cells in culture

John Galivan, Malgorzata Balińska, John M. Whiteley

Journal:

Archives of Biochemistry and Biophysics

Year:

1982

Language:

english

File:

PDF, 613 KB

english, 1982

10

Stabilization of cholic acid uptake in primary cultures of hepatocytes by dexamethasone and tocopherol

Journal:

Archives of Biochemistry and Biophysics

Year:

1982

Language:

english

File:

PDF, 269 KB

english, 1982

11

Prevention of colchicine toxicity to cultured rat hepatocytes by glucagon, hydrocortisone and insulin

Journal:

Experimental Cell Research

Year:

1981

Language:

english

File:

PDF, 569 KB

english, 1981

12

Exploitation of folate and antifolate polyglutamylation to achieve selective anticancer chemotherapy

John J. McGuire, Takashi Tsukamoto, Barry P. Hart, James K. Coward, Thomas I. Kalman, John Galivan

Journal:

Investigational New Drugs

Year:

1996

Language:

english

File:

PDF, 557 KB

english, 1996

13

The properties of the secreted γ-glutamyl hydrolases from H35 hepatoma cells

Ying Wang, Zenia Nimec, Thomas J. Ryan, James A. Dias, John Galivan

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1993

Language:

english

File:

PDF, 854 KB

english, 1993

14

Glutamyl hydrolase: pharmacological role and enzymatic characterization

John Galivan, Thomas J Ryan, Karen Chave, Myung Rhee, Rong Yao, Dezhong Yin

Journal:

Pharmacology & Therapeutics

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

15

Effect of substrate analogs on the circular dichroic spectra of thymidylate synthetase from Lactobacillus casei

Galivan, John H., Maley, Gladys F., Maley, Frank

Journal:

Year:

1975

Language:

english

File:

PDF, 856 KB

english, 1975

16

MEMBRANE CHARACTERISTICS OF PRIMARY HEPATOCYTE CULTURES AND A STABLE HEPATOCARCINOMA CELL LINE

John Galivan, Anthony Tarentino, William Samsonoff

Journal:

Annals of the New York Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 2.05 MB

english, 1980

17

Transport of methotrexate by primary cultures of rat hepatocytes: Stimulation of uptake in vitro by the presence of hormones in the medium

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 886 KB

english, 1981

18

Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients: Association with hepatic folate deficiency and formation of polyglutamates

Joel M. Kremer, John Galivan, Anita Streckfuss, Barton Kamen

Journal:

Arthritis & Rheumatism

Year:

1986

Language:

english

File:

PDF, 347 KB

english, 1986

19

Regulatory aspects of the glutamylation of methotrexate in cultured hepatoma cells

Zenia Nimec, John Galivan

Journal:

Archives of Biochemistry and Biophysics

Year:

1983

Language:

english

File:

PDF, 908 KB

english, 1983

20

Factors controlling the concentrations of methotrexate in cultured hepatic cells

John Galivan, Malgorzata Balinska, Zenia Nimec, M.Patricia Fox

Journal:

Advances in Enzyme Regulation

Year:

1982

Language:

english

File:

PDF, 494 KB

english, 1982

21

Studies on the reactivity of the essential cysteine of thymidylate synthetase

John Galivan, James Noonan, Frank Maley

Journal:

Archives of Biochemistry and Biophysics

Year:

1977

Language:

english

File:

PDF, 940 KB

english, 1977

22

Biological properties of fluoroglutamate-containing analogs of folates and methotrexate with altered capacities to form poly (γ-glutamate) metabolites

John J. McGuire, Barry P. Hart, William H. Haile, Kathryn J. Magee, Myung Rhee, Wanda E. Bolanowska, Cynthia Russell, John Galivan, Brajeswar Paul, James K. Coward

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.11 MB

english, 1996

23

Protective effect of the pteroylpolyglutamates and phosphate on the proteolytic inactivation of thymidylate synthetase

John Galivan, Frank Maley, Charles M. Baugh

Journal:

Archives of Biochemistry and Biophysics

Year:

1977

Language:

english

File:

PDF, 846 KB

english, 1977

24

Purification and properties of T2 bacteriophage-induced thymidylate synthetase

Galivan, John, Maley, Gladys F., Maley, Frank

Journal:

Year:

1974

Language:

english

File:

PDF, 1.94 MB

english, 1974

25

Recovery of sealed H35 hepatoma cells in monolayer culture following lysolecithin permeabilization

Journal:

Methods in Cell Science

Year:

1983

Language:

english

File:

PDF, 327 KB

english, 1983

26

Normal and warfarin-resistant rat hepatocyte metabolism of vitamin K 2,3-epoxide: Evidence for multiple pathways of hydroxyvitamin K formation

Leena S. Trivedi, Myung Rhee, John H. Galivan, Michael J. Fasco

Journal:

Archives of Biochemistry and Biophysics

Year:

1988

Language:

english

File:

PDF, 626 KB

english, 1988

27

Hormonal alteration of methotrexate and folate polyglutamate formation in cultured hepatoma cells

Journal:

Archives of Biochemistry and Biophysics

Year:

1984

Language:

english

File:

PDF, 687 KB

english, 1984

28

The effect of methionine on methotrexate metabolism in rat hepatocytes in monolayer culture

Myung S. Rhee, Thomas B. Johnson, David G. Priest, John Galivan

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1989

Language:

english

File:

PDF, 884 KB

english, 1989

29

Dihydrofolate-mediated reversal of methotrexate toxicity to hepatoma cells in vitro

Kruger-McDermott, Claire, Balinska, Malgorzata, Galivan, John

Journal:

Year:

1986

Language:

english

File:

PDF, 385 KB

english, 1986

30

Site-directed mutagenesis establishes cysteine-110 as essential for enzyme activity in human γ-glutamyl hydrolase

CHAVE, Karen J., GALIVAN, John, RYAN, Thomas J.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 126 KB

english, 1999

31

Inhibition of mammalian thymidylate synthase by 10-formyltetrahydropteroylpolyglutamate

Malgorzata Balinska, Myung Rhee, John M. Whiteley, David G. Priest, John Galivan

Journal:

Archives of Biochemistry and Biophysics

Year:

1991

Language:

english

File:

PDF, 469 KB

english, 1991

32

Glutamylation of methotrexate in hepatoma cells in vitro: Regulation and the development of specific inhibitors

John Galivan, Zenia Nimec, James K. Coward, John J. McGuire

Journal:

Advances in Enzyme Regulation

Year:

1985

Language:

english

File:

PDF, 493 KB

english, 1985

33

Demonstration of separate binding sites for the folate coenzymes and deoxynucleotides with inactivated Lactobacillus casei thymidylate synthetase

John H. Galivan, Frank Maley, Charles M. Baugh

Journal:

Biochemical and Biophysical Research Communications

Year:

1976

Language:

english

File:

PDF, 435 KB

english, 1976

34

Methotrexate analogs. 22. Synthesis, dihydrofolate reductase affinity, cytotoxicity, and in vivo antitumor activity of some putative degradation products of methotrexate-poly(L-lysine) conjugates

Rosowsky, Andre, Forsch, Ronald A., Freisheim, James H., Galivan, John, Wick, Michael

Journal:

Journal of Medicinal Chemistry

Year:

1984

Language:

english

File:

PDF, 945 KB

english, 1984

35

The Temporal Expression of T2r+Bacteriophage Genes in vivo and in vitro

Robert B. Trimble, John Galivan and Frank Maley

Journal:

Proceedings of the National Academy of Sciences

Year:

1972

Language:

english

File:

PDF, 1.00 MB

english, 1972

36

Effects of D,L-4-fluoroglutamic acid on glutamylation of methotrexate by hepatic cells in vitro

John Galivan, James K. Coward, John J. McGuire

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 406 KB

english, 1985

37

Amino Acid Sequence at the FdUMP Binding Site of Thymidylate Synthetase

Ronald L. Bellisario, Gladys F. Maley, John H. Galivan and Frank Maley

Journal:

Proceedings of the National Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 1.23 MB

english, 1976

38

Identification of single nucleotide polymorphisms in the human γ-glutamyl hydrolase gene and characterization of promoter polymorphisms

Karen J Chave, Thomas J Ryan, Stacey E Chmura, John Galivan

Journal:

Year:

2003

Language:

english

File:

PDF, 239 KB

english, 2003

39

Synthesis of N-[N-(4-deoxy-4-amino-10-methylpteroyl)-4-fluoroglutamyl]-.gamma.-glutamate, an unusual substrate for folylpoly-.gamma.-glutamate synthetase and .gamma.-glutamyl hydrolase

Licato, Nicholas J., Coward, James K., Nimec, Zenia, Galivan, John, Bolanowska, Wanda E., McGuire, John J.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 881 KB

english, 1990

40

Characteristics of methotrexate polyglutamate formation in cultured hepatic cells

Malgorzata Balinska, Zenia Nimec, John Galivan

Journal:

Archives of Biochemistry and Biophysics

Year:

1982

Language:

english

File:

PDF, 957 KB

english, 1982

41

The properties and function of γ-glutamyl hydrolase and poly-γ-glutamate

Ying Wang, James A. Dias, Zenia Nimec, Robert Rotundo, Brigid M. O'Connor, James Freisheim, John Galivan

Journal:

Advances in Enzyme Regulation

Year:

1993

Language:

english

File:

PDF, 596 KB

english, 1993

42

Regulation of methotrexate polyglutamate accumulation in vitro: effects of cellular folate content

John Galivan, Zenia Nimec, Malgorzata Balinska

Journal:

Biochemical Pharmacology

Year:

1983

Language:

english

File:

PDF, 552 KB

english, 1983

43

Human $\gamma $-glutamyl Hydrolase: Cloning and Characterization of the Enzyme Expressed in vitro

Rong Yao, Erasmus Schneider, Thomas J. Ryan and John Galivan

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.01 MB

english, 1996

44

Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysis

Galivan, John H., Maley, Gladys F., Maley, Frank

Journal:

Year:

1976

Language:

english

File:

PDF, 873 KB

english, 1976

45

Structural organization of the human γ-glutamyl hydrolase gene

Dezhong Yin, Karen J. Chave, Christopher R. Macaluso, John Galivan, Rong Yao

Journal:

Year:

1999

Language:

english

File:

PDF, 361 KB

english, 1999

46

Cloning of mouse γ-glutamyl hydrolase in the form of two cDNA variants with different 5′ ends and encoding alternate leader peptide sequences

Taito Esaki, Krishnendu Roy, Rong Yao, John Galivan, F.M Sirotnak

Journal:

Year:

1998

Language:

english

File:

PDF, 496 KB

english, 1998

47

The Chromophore and Polypeptide Composition of Aplysia Ink

Robert MacColl, John Galivan, Donald S. Berns, Zenia Nimec, Deborah Guard-Friar and David Wagoner

Journal:

Biological Bulletin

Year:

1990

Language:

english

File:

PDF, 432 KB

english, 1990

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